and anti-RNA polymerase antibody. The purpose of this study was to investigate tumor necrosis factor (TNF) polymorphisms in scleroderma, with the specific aim of determining whether TNF ...

The signs and symptoms of scleroderma can be mistaken ... 70 (positive in 30% of SSc patients), is specific to SSc. Two thirds of patients with this antibody have diffuse SSc and pulmonary ...

Antibody treatment also reversed metabolic abnormalities in the scleroderma model ... Michigan-Mayo team is now developing ...

The type of scleroderma impacts the likelihood of specific facial symptoms, but all forms can cause tight, hard areas of skin, texture changes, discoloration, the appearance of blood vessels ...

Common conditions such as Parkinson’s and Alzheimer’s diseases, epileptic encephalopathy and amyotrophic lateral sclerosis ... the antibodies need to be well characterized, highly specific ...

"We know B cells -- the cells that make antibodies ... and Sanofi/Genzyme. A specific autoantibody signature was seen in a ...

1). RubrYc’s lead programs include RTX-002, an anti-PD-1 agonist for serious autoimmune diseases such as systemic lupus erythematosus and multiple sclerosis, and RTX-003, an anti-CD25 antibody ...