Key Laboratory of Smart Biomaterials of Zhejiang Province and Key Laboratory of Biomass Chemical Engineering of the Ministry of Education of China, College of Chemical and Biological Engineering, ...

Calcium-uptake and ATPase studies carried out on fragmented sarcoplasmic reticulum from muscle of patients with Duchenne dystrophy showed low initial and total calcium uptake, low ATPase activity ...

A recent study of 326 RyR2 mutations including control (non-pathogenic) and CPVT-associated groups found that many of the mutations were located in four CPVT hot spot regions: 10.7% in region I ...

The endoplasmic reticulum (ER) is the site at which secreted proteins (such as the hormone insulin) and membrane-bound proteins are folded. ATP-dependent chaperones within the ER help proteins fold.

The opening of SOCCs is regulated by the filling state of the intracellular Ca 2+ store, the sarcoplasmic reticulum, which communicates to the plasma membrane channels through the Stromal Interaction ...