cardiomyocytes transition from glycolytic to oxidative metabolism to match the increased need for energy by a rapidly growing body and the T-tubules and the sarcoplasmic reticulum form to manage Ca+2 ...

SARCOTUBULAR, fragments prepared from homogenates of skeletal muscle are able to sequester vigorously calcium ions if ATP is available, and they show the activity of Mg-ATPase and Ca-ATPase which ...

The heart is a highly sex-biased organ, as sex shapes innumerable aspects of heart health and disease. Sex chromosomes and sex hormones —testosterone, progesterone, and estrogen— establish and ...

Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore (A.B., A.K.-K.) Department of Biochemistry and Molecular ...

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Ginsenosides (Rb1, Rg3, Re) and TGS can effectively target different molecular mechanisms, such as the regulation of calcium ion concentration, inhibition of caspase-dependent apoptosis pathway, ...

Calcium homeostasis plays an essential role in maintaining excitation–contraction coupling (ECC) in cardiomyocytes, including calcium release, recapture, and storage. Disruption of calcium homeostasis ...