addenbrookes.nhs.uk Background and aims: Genetic association between Crohn’s disease (CD) and OCTN1 (SLC22A4) C1672T/OCTN2 (SLC22A5) G−207C variants in IBD5 has recently been reported. These genes ...

and OCTN2 (SLC22A5 −207G→C) variants within the IBD5 locus have been associated with susceptibility to adult onset Crohn’s disease (CD), but their contribution in children has not been examined.

Genome-wide association (GWA) studies have dramatically influenced our ability to identify genetic risk factors for complex immune-mediated diseases. We provide the information necessary for ...

During the first two trimesters of pregnancy, the maternal metabolism continuously adapts, with accretion of fat stores deriving from aliments and then shifting to an accelerated catabolism of ...

In this scientific statement from the American Heart Association, experts in the field of cardiomyopathy (heart muscle disease) in children address 2 issues: the most current understanding of the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Solute carrier (SLC) transporters govern most ...

GIST outpatients who received imatinib mesylate (Gleevec, Novartis, Switzerland) between July 2020 and March 2021 at the First Affiliated Hospital of Soochow University were selected. Upon enrollment, ...

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