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Nature26d
Structure and lipid transport mechanism of a StAR-related domain
The role of StAR in this process is unique, and other types of cholesterol transporter, such as sterol carrier protein-2 (SCP2), cannot replace it. Here, the structure of the START domain of MLN64 ...
Nature28d
Gene redundancy and pharmacological gene therapy: Implications for X-linked adrenoleukodystrophy
Aubourg) and human SCP2 (SCP2 antibody was a gift from J. Strauss). Enhanced chemiluminescence (SuperSignal Substrate; Pierce, Rockford, Illinois) was used to detect bound antibody ...
ahajournals.org6d
Abstract 12944: Sterol Carrier Protein-2 (SCP2) Deficiency Attenuates Western Diet (WD)-Induced Hyperlipidemia, Hepatic Steatosis and Bile Acid Composition in LDLR-/- Mice
Appropriate delivery of free cholesterol (FC) to subcellular organelles is essential for cholesterol metabolism and SCP2 is one of the intracellular proteins that facilitates this process. Within ...
C&EN14d
Characterization of the Drug Binding Specificity of Rat Liver Fatty Acid Binding Protein
†Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences. ‡Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences. Article Views are the ...
C&EN24d
Liver Fatty Acid-Binding Protein Colocalizes with Peroxisome Proliferator Activated Receptor α and Enhances Ligand Distribution to Nuclei of Living Cells
Department of Physiology and Pharmacology, Texas A&M University, College Station, Texas 77843-4466, Department of Biochemistry and Molecular Biology, Oregon Graduate Institute of Science and ...