The RanGTP–RanGDP gradient across the nuclear membrane is generated by the action of two regulators, RanGEF (Ran-GDP-exchange factor) in the nucleus and RanGAP (Ran-GTPase-activating protein ...

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1 Department of Biology, McGill University, Montreal, QC, Canada 2 Department of Biology, Concordia University, Montreal, QC, Canada Cytokinesis is required to physically cleave a cell into two ...

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