Most antisense oligonucleotide experiments are performed with molecules containing RNase H-competent backbones. However, RNase H may cleave nontargeted mRNAs bound to only partially complementary ...

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

This study presents an important finding on the role of GATA4 in aging and OA-associated cartilage pathology. The evidence supporting the conclusions is compelling, with rigorous in vitro and in vivo ...

The question mark symbolizes potential unidentified component(s). Activation of endogenous RNase H activity was accomplished by adding each cDNA oligo (1 μM) directly to splicing reactions and ...

Triple H is opening up about the life-changing health scare that almost ended everything—and how he now sees it as a blessing. The WWE executive, whose real name is Paul Levesque, nearly died in ...

I remember the heat. A dry, suffocating torrent. The blazing, burning sun baking the tarmac. No clouds, no trees, just a furnace of hate. I feel the hate. I remember the heat. I remember the dust.

The dual-motor four-wheel drive system allows the SUV to accelerate from 0 to 100 km/h in 3.23 seconds, with a top speed of 253 km/h. According to Xiaomi, magnetic steel segmentation and topology ...

Although RNase H2 is absent from short telomeres, it is quickly compensated for by the recruitment of RNase H1 and Sen1. The recruitment of RNase H1 is essential to allow for the loading of Rad51, ...

Faye Tozer looked radiant as she gave her first TV interview since her split from husband of 16 years - but H stole the show with a jaw-dropping reveal about his famous blond hair. Pop group ...

The primary tenure-track faculty, research-track faculty and secondary faculty in the Saint Louis University Department of Molecular Microbiology and Immunology oversee active independent research ...

We collaborate with the world's leading lawyers to deliver news tailored for you. Sign Up for any (or all) of our 25+ Newsletters. Some states have laws and ethical rules regarding solicitation ...