Most of the major conditions required for RNA to replicate, possibly the key stage in kick-starting life, were probably met ...

The RNA polymerase is responsible for the replication of viral genetic material and the activation of viral genes, and is ...

Nobel Laureate and University of Chicago professor Jack Szostak delivered two lectures on the origin of life to an audience of professors, graduate, and undergraduate students the Monday and Tuesday ...

To fight the virus that causes influenza, one of the avenues being explored by scientists is the development of drugs capable of destabilizing its genome, which is made up of eight RNA molecules.

The accuracy of these copies determines the health and inherited features of the nascent cells, so it is essential that the process of DNA replication be as accurate as possible (Figure 1).

During DNA replication, the complementary base pairing ensures faithful copying of the genetic material. In RNA, cytosine also pairs with guanine. However, RNA is typically single-stranded and serves ...

Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...

Several antiviral and anticancer drugs target the incorporation of adenine into DNA or RNA. For example, some nucleoside analog drugs, such as vidarabine and fludarabine, mimic adenine and interfere ...

Novel technology enables discovery, which could help predict tumour recurrence Researchers from the Fred Hutch Cancer Centre, ...