A Prescription Drug User Fee Act target date of May 27, 2025 has been assigned to the application. The Food and Drug Administration (FDA) has accepted for Priority Review the New Drug Application ...

"These findings illuminate a critical mechanism that connects local synaptic activity to the broader gene expression changes necessary for learning and memory," said Mark Dell'Acqua, professor of ...

The international team describes their results and the underlying molecular mechanism in Cell Metabolism. Ergothioneine is a natural compound found in certain fungi such as oyster or shiitake ...

Identifying when a patient employs a defense mechanism, such as projection, for instance, can be a helpful catalyst in the therapeutic process. Schools of therapy other than Freud's psychoanalytic ...

Identifying when a patient employs a defense mechanism, such as projection, for instance, can be a helpful catalyst in the therapeutic process. Schools of therapy other than Freud's psychoanalytic ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Metabolic requirements of dividing hepatocytes ...

We documented a shift from a fast, reversible mechanism driven by methylation in central metabolic pathways to a slower, stable mechanism involving mutations in key metabolic genes. Both mechanisms ...

In this important work, Lodhiya et al. provide evidence that excessive ATP underlies the killing of the model organism Mycobacterium smegmatis by two mechanistically-distinct antibiotics. The data are ...

Laboratory of Precision Nanomedicine, Shmunis School of Biomedicine and Cancer Research, Tel Aviv University, Tel Aviv-Yafo 69978, Israel Department of Materials Sciences and Engineering, Tel Aviv ...

The pyruvate formed is reduced by NADH in a reaction catalyzed ... AST in the sample catalyzes the transfer of an amino group between L-aspartate and 2-oxoglutarate to yield oxaloacetate and ...