In prokaryotic cells, DNA bundles together in a region called the nucleoid. Primitive organelles, such as micro-compartments found in some bacteria, help organize cellular processes by concentrating ...

This engineered genome will help experts tailor organisms to fit the needs of their ever-changing environments.

Cell contents Cytoplasm, cell organelles include mitochondria ... plasmids are found in a few simple eukaryotic organisms. Prokaryotic cell DNA is a single molecule, found free in the cytoplasm ...

Previous experiments had been done on prokaryotes (single-celled organisms ... celled eukaryotic organisms (which have a nucleus and organelles with distinct functions). This synthetic genome ...

However, mitochondria have preserved a great deal of their prokaryotic heritage. This is reflected in the pathways of protein sorting within the organelles. For example, proteins of the space between ...

Department of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, 35043 Marburg, Germany Center for Synthetic Microbiology (SYNMIKRO), 35043 Marburg, Germany ...