Prions, mysterious shape-shifting proteins, can lead to brain disorders such as Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy, "mad cow disease" in cattle, yet they can also ...

Transmissible spongiform encephalopathy or prion disease is triggered by the conversion from cellular prion protein to pathogenic prion protein. Notably, C-transmembrane form of prion protein and ...

Bovine spongiform encephalopathy (BSE). Commonly called “mad cow disease,” this type of prion disease affects cows. Humans who consume meat from cows with BSE can be at risk for vCJD.

Prions are highly robust and infectious proteins, most notable for their central role in bovine spongiform encephalopathy, commonly called mad cow disease. But very little is known about how ...

Prions, the infectious agents responsible for transmissible spongiform encephalopathies, consist mainly of the misfolded prion protein (PrPSc). The unique mechanism of transmission and the appearan ...

Mammalian transmissible spongiform encephalopathy (prion) and amyloid diseases seem to involve the self-propagation of abnormal fibrillar or sub-fibrillar protein aggregates. Similar processes ...

Prion diseases, such as bovine spongiform encephalopathy ('mad cow disease'), are lethal neurodegenerative infectious diseases that affect humans and other mammals and for which there is currently ...

In the 1980s, we learned that cows could develop bovine spongiform encephalopathy, or mad cow disease, from prions—which may have been caught from prion-infected sheep.

A variant form of Creutzfeldt-Jakob disease has long been tied to eating beef from cattle infected with mad cow disease, or bovine spongiform encephalopathy, which is another prion disorder.