Multiomic profiling of LRRC15 in triple negative breast cancer (TNBC). A phase 1b study of Plk1 inhibitor onvansertib in combination with paclitaxel in metastatic triple-negative breast cancer (mTNBC) ...

A phase 1b study of Plk1 inhibitor onvansertib in combination with paclitaxel in metastatic triple-negative breast cancer (mTNBC) patients. This is an ASCO Meeting Abstract from the 2025 ASCO Annual ...

A double-strand DNA break (DSB) occurs or arises when both strands of the DNA duplex are severed, often as the result of ionizing radiation. They are particularly deleterious as the DNA ends can ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Sister-chromatid cohesion mediated by the ...

This study provides valuable findings that MK2 inhibitor CMPD1 can inhibit the growth, migration and invasion of breast cancer cells both in vitro and in vivo. The evidence supporting the claims of ...

Gastrointestinal microbiota and inflammasomes interplay in health and disease: a gut feeling ...