Cardiac stem ... of paracrine factors released by MSCs. These factors can enhance angiogenesis (the formation of new blood vessels), reduce cell death, and improve overall heart function[3].

Cardiac cell therapy for chronic heart failure may be able to target fibroblast behavior in a paracrine fashion ... and is challenged by the miscellaneous functions of the TGF-β pathway and its dual ...

EVs, and particularly exosomes, are implicated in the transfer of mRNAs, microRNAs (miRNAs), proteins and lipids between cells and thus are able to modify the function of recipient cells. Exosomes ...

Stem cell therapy is emerging as a potential treatment for different conditions in endocrinology, including diabetes and ...

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...

This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...

Messenger RNA can travel between different types of stem cells through tunnel-like structures, as revealed by a new study. By ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

The novel drug CT-179 ... How Healthy Stem Cells Turn Into Oral Cancer Feb. 4, 2025 — Researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into ...

Get Instant Summarized Text (Gist) A new approach, PERISCOPE, integrates Cell Painting and Optical Pooled Screening to enable genome-scale CRISPR screens, linking cell morphology to gene function ...

In a new study published in Cell Reports, Finnish researchers show that pituitary macrophages, the immune cells located in ...