It will also support initial trials of CD70-targeted PRO1160, PTK7-targeted PRO1107, and bispecific ADC PRO1286. New investors in the round included Nextech Invest, T Rowe Price Associates, ...

Efficient cytosolic delivery of nucleic acid therapeutics remains a central challenge for DNA nanostructure-based biomedical applications. Here, we report a programmable DNA origami delivery ...

Auristatins, synthetic analogues of the antineoplastic natural product Dolastatin 10, are ultrapotent cytotoxic microtubule inhibitors that are clinically used as payloads in antibody–drug conjugates ...