After a grueling 10-inning game, the Rebels’ first-ever trip to the Women’s College World Series ended Friday night with a loss to 16th-seeded Oregon.

The progressive worsening of disc degeneration and related nonspecific back pain are prominent clinical issues that cause a tremendous economic burden. Activation of reactive oxygen species (ROS) ...

Pyruvate dehydrogenase kinases (PDKs) are overexpressed in most cancer cells and are responsible for aberrant glucose metabolism. We previously described bis(4-morpholinyl thiocarbonyl)-disulfide ...

The antitumour effects of rapamycin are mediated primarily through S6K inhibition in our studies. The recent report that KRAS-induced pancreatic cancer was substantially reduced in mice expressing an ...

Background Tumourigenesis in right-sided and left-sided colons demonstrated distinct features. Objective We aimed to characterise the differences between the left-sided and right-sided adenomas (ADs) ...

Perineural invasion (PNI) is a significant biological characteristic of pancreatic cancer, manifested by the infiltration of tumor cells into neural tissues, facilitating their spread and metastasis ( ...

(E–H) Immunoblots showing the phosphorylation of (E) AKT, mTOR, S6K, and S6, (F) EGFR, (G) STAT3, and (H) Girdin. ( I ) Proposed scheme of anticancer mechanism of 1a via targeting Girdin. 1a engages ...