PDK1-KO hearts showed reduction of Akt and SGK activities, upregulation of Bax protein and endoplasmic reticulum stress signals, which were the potential causes of cardiomyocyte apoptosis.

Background— Cardiovascular disease is the leading cause of death for both men and women in the United States and the world. A profound pattern exists in the time of day at which the death occurs; it ...

The tumor microenvironment (TME) is characterized by distinct metabolic adaptations that not only drive tumor progression but also profoundly influence immune responses. Among these adaptations, ...

1 State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China 2 Haihe Laboratory of Modern Chinese Medicine, Tianjin University of ...

M. El-Sobky, R. Rijal, R. Gomer, Collected data for polyphosphate chemorepulsion. Figshare. https://figshare.com/s/27dcc330cb24d1a33c17. Deposited 21 March 2025.