The FDA has accepted for review the NDA for linerixibat for the treatment of cholestatic pruritus in patients with primary biliary cholangitis.

EU kicks off review of GSK's linerixibat in PBC. GSK's drug for severe itching in patients with autoimmune liver disease PBC is now under review in the EU and US, as Mirum Pharma tries to catch up.

GSK said that linerixibat has a chance of becoming the first 'global' therapy for itch associated with PBC – in other words, it may be able to be used as a first- or later-line therapy.

“Relentless itch is present in the majority of patients with PBC and is a symptom that affects sleep, mental health, and quality of life,” said Khavandi, in a May press release. “With linerixibat, we ...

The PBC Make-A-Wish awards were renamed the LeeAnn Noble Make-A-Wish Awards following the 2013-14 season. Noble was a women's golfer at North Georgia and former wish recipient from Make-A-Wish. She ...

Histopathological study of primary biliary cirrhosis and the effect of ursodeoxycholic acid treatment on histology progression. Hepatology 29 , 1007–1012 (1999). Article CAS Google Scholar ...

An armpit rash can be uncomfortable or even painful. Often, the cause is mysterious, but you can treat the conditions at home. Sometimes, however, an armpit rash is severe enough to require a trip ...

Disney rash is a type of vasculitis, also called golfer's or hiker's rash because it's strongly linked to the kind of walking these activities inspire. Learn more.

Livestreaming from Michelob Ultra Arena in Las Vegas, NV, watch Plant vs Resendiz boxing live on pay-per-view: Here's where to find and watch online.

Heat rash is a skin condition that often affects children and adults in hot, humid weather conditions. You can develop heat rash when your pores become blocked and sweat can’t escape.

Heat rash: In hot weather, especially in hot and humid weather, sweat can be trapped under the skin, which can result in prickly heat. Prickly heat results in red bumps, itching, and a prickly ...