Scientists have recently shed some light on exactly why elephants, one of the biggest animals on the planet, paradoxically ...

We next tested whether IFI 16 and p53 can interact while p53 is bound to DNA. Gel shift assays were performed using double stranded oligonucleotides derived from the p21 waf1/Cip1 promoter ...

The p53 tumor suppressor gene is a sequence-specific transcription factor that activates the expression of genes engaged in promoting growth arrest or cell death in response to genotoxic stress.

Cancer took just about everyone in journalist Larry Ingrassia’s family, except him. His book unpacks his family’s ...

SPEAKER Ferdinand Martin G. Romualdez on Sunday instructed the House think tank to immediately conduct a thorough study on the viability of institutionalizing the national government’s P20-per-kilo ...

PMV Pharmaceuticals, Inc. (“PMV Pharma”; Nasdaq: PMVP), a precision oncology company pioneering the discovery and development of small molecule, tumor-agnostic therapies targeting p53, today announced ...

This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

Some BBQ sauces are healthier than others. Some are just downright unhealthy and bad for your body. Here are the worst ...

Vesicor Therapeutics, a San Gabriel-based biotech firm developing p53-based cancer treatments, is set to go public through a $70 million merger with SPAC Black Hawk Acquisition Corp. The combined ...

Smart Communications Inc. is banking on growing 5G usage and device adoption to help stabilize its wireless revenues, ...

A phase I multicenter study to assess the safety, tolerability, and immunogenicity of mRNA-4157 alone in patients with resected solid tumors and in combination with pembrolizumab in patients with ...

House Speaker Martin Romualdez has expressed optimism with the potential institutionalization of the Marcos administration’s ...