We next tested whether IFI 16 and p53 can interact while p53 is bound to DNA. Gel shift assays were performed using double stranded oligonucleotides derived from the p21 waf1/Cip1 promoter ...

SPEAKER Ferdinand Martin G. Romualdez on Sunday instructed the House think tank to immediately conduct a thorough study on the viability of institutionalizing the national government’s P20-per-kilo ...

Some BBQ sauces are healthier than others. Some are just downright unhealthy and bad for your body. Here are the worst ...

A phase I multicenter study to assess the safety, tolerability, and immunogenicity of mRNA-4157 alone in patients with resected solid tumors and in combination with pembrolizumab in patients with ...

House Speaker Martin Romualdez has expressed optimism with the potential institutionalization of the Marcos administration’s ...

PLDT Inc. expects its enterprise business to continue driving growth amid rising demand for connectivity and technology solutions. “Obviously, it is a very tough market right now, but I also think ...

A NEW nationwide study reveals meaningful improvements in hunger levels among low-income households supported by the 'Walang ...

After SCH58500 treatment, 3–11–fold elevations of p21 expression were observed in tumor xenografts containing nonfunctional p53 (MDA-MB-468, MDA-MB-231, MIAPaCa2, DU-145, and SK-OV-3), but no ...

Pump prices are set for mixed movements this week: gasoline price is set to increase for a third straight week starting ...

Brdar, Osterburg, Munick, et al. present an interesting cellular and biochemical investigation of different p53 isoforms. The authors investigate the impact of different isoforms on the in-vivo ...

Researchers at the University of Michigan Rogel Cancer Center have found a promising new way to stop prostate cancer from ...

The major off- targeting effect is mediated through p53 activation, as detected through the transferase- mediated dUTP nick end labeling assay, acridine orange, and p21 transcriptional activation ...