This study presents an important discovery regarding the diversity and evolution of gall-forming microbial effectors. Supported by convincing computational structural predictions and analyses, the ...

DNA hydrogels are biocompatible drug delivery systems for targeted therapeutic interventions. Conventional DNA hydrogels, formed with many DNA nanostructure units, lead to increased preparation costs ...

Innovative Takumi-shaped DNA hydrogels exhibit prolonged retention and drug release, showcasing their potential as ...

Hydrogels are polymeric materials with three-dimensional network structures containing large amounts of water. They serve as sustained-release drug delivery systems as they can encapsulate various ...

By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating ...

DNA has gained significant attention as a promising hydrogel material thanks to its customizable physicochemical properties, ...

Due to the helical structure of DNA, there is an angular ... Quantum chemical calculations were then conducted on selected nucleotide subsets, focusing on the nitrogen atom positions within ...

Structural variation is a change in the structure of an organism's genome ... you could think of a single nucleotide variant as a typo, whereas a structural variant is like ripping out a whole page.

They then deployed genome sequencing to analyse the genetic effects of these structural variations on cell survival. It showed that as long as essential genes remain intact, our genomes can tolerate ...

Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, United States Department of Biochemistry and Structural Biology, University of ...