The Notch signaling pathway regulates important cellular processes involved in stem cell maintenance, proliferation, development, survival, and inflammation. These responses to Notch signaling ...
Notch signaling has been identified as a key regulatory pathway in patterning the endocardium through activation of endothelial-to-mesenchymal transition (EMT) in the atrioventricular canal (AVC) and ...
Recent studies have illuminated the connection between CD133 and key signaling pathways, including PI3K/AKT, WNT/β-catenin, and Notch, which govern cell cycle checkpoints and tumor progression. CD133 ...
Notch- and S1P-signaling may be components of this maturation process, but spatial transcriptomic analyses are needed to reveal key differences in signaling- pathway gene expression which confer a ...
CD8+ T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathway—with therapeutic ...
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Researchers discover key signaling pathway involved in atherosclerotic plaquesCD8+ T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathway - with therapeutic potential.
Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone ...
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Interferon pathway activation identified as key driver in OPLL pathogenesisRecent insights reveal the potential role of interferon (IFN) signaling in the pathogenesis of OPLL, particularly the type I IFN pathway, which is known to play a role in innate immune responses and ...
MIT researchers suggests a potential molecular strategy for treating fragile X syndrome by enhancing NMDA subunit function.
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