Findings suggest that slack titin molecules drive muscle disease, potentially through mechanisms shared with other mechanical proteins.

nebulin-related anchoring protein; p62/SQSTM1, p62/sequestosome-1; PICOT, protein kinase C–interacting cousin of thioredoxin; RAF1, rapid accelerated fibrosarcoma-1; and TCAP, titin Cap (illustration ...

Medical research involves research in a wide range of fields, such as biology, chemistry, pharmacology and toxicology with the goal of developing new medicines or medical procedures or improving ...

Genetics research is the scientific discipline concerned with the study of the role of genes in traits such as the development of disease. It has a key role in identifying potential targets for ...

Transverse tubules (TTs) are tubular invaginations of myocyte membrane forming junctions with sarcoplasmic reticulum and are essential for excitation-contraction coupling. Although it is known that ...

College of Biological Engineering, The Key Laboratory of Science and Technology for Aquaculture and Food Safety, Jimei University, Xiamen, China, 361021, and Faculty of Fisheries, Nagasaki University, ...