In persons with myophosphorylase deficiency, the serum CK may elevate to up five times the upper limit of normal without symptoms. There is no rise in lactate due to complete failure of glycogen ...

IN 1951 McArdle 1 described a patient with a hitherto unrecognized muscle disorder in which marked weakness, cramping pain and prolonged stiffness of muscles were produced by moderate degrees of ...

7 Department of Neurology, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK 8 Department of Neurology, King's College Hospital and King's College School of Medicine, London, UK Correspondence to Dr ...