The incurable bone marrow cancer “multiple myeloma” often develops unnoticed in the bone marrow over decades. In advanced stages, lesions form that can destroy the bone and spread to other parts of ...

In turn, growth factors released by the increased bone resorptive process also increase the growth of myeloma cells, creating a vicious cycle of bone destruction and tumor expansion. The receptor ...

Get Instant Summarized Text (Gist) When blood cancer cells, such as those in multiple myeloma, exit the bone marrow, they become highly diverse, altering the immune response in the affected areas ...

For patients with newly diagnosed multiple myeloma (NDMM) receiving dexamethasone ... Rahul Banerjee, M.D., from the Fred Hutchinson Cancer Center in Seattle, and colleagues conducted a secondary ...

Tumor suppressor miRNAs are methylated in myeloma. Therefore, miR-34b/c methylation is acquired at relapse. miR-203 methylation is frequent in both MGUS and myeloma, and hence is an early event in ...