SPP1+ macrophages identified as key drivers and therapeutic targets in colorectal cancer progression
(A) Volcano plot of DEGs in monocytes/macrophages between NC and CRC samples in the GSE164552 dataset. (B) Venn diagrams of common DEGs up- or down-regulated across the six scRNA-seq datasets (NC vs.
SPP1+ Macrophages Identified as Key Drivers and Therapeutic Targets In Colorectal Cancer Progression
Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related deaths worldwide.
Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...
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