Researchers from the Mitochondrial Medicine Program at Children's Hospital of Philadelphia (CHOP) have better characterized a spectrum of what were classically considered discrete mitochondrial DNA ...
Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...
Furthermore, complications of mitochondrial disease and clinical phenotype variations in patients with similar levels of heteroplasmy are common. Thus, identifying the cause of this variation is ...
Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China CAS Key Laboratory for ...
School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, P. R. China State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing ...
The mitochondrial DNA (mtDNA) in eukaryotic cells encodes a ... of mtDNA in yeast colonies partitioned among individual cells? Given the evidence of heteroplasmy in ‘mixed’ structure colonies, we were ...
Herein, we will highlight some of the major findings obtained using iPSC-CMs and we will explore the pathophysiological causality of both mtDNA and nuclear DNA gene mutations in causing mitochondrial ...
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