The second dataset, GSE21036, consists of the expression data of miRNAs of 42 Samples (including 14 metastatic prostate tumours and 28 normal prostate tissues) generated on the GPL8227 platform ...

Methods We performed microRNA (miRNA) and messenger RNA (mRNA) profiling using microarray in cells treated with bile acids. Data integration of the miRNA/mRNA profiles with gene ontology (GO) analysis ...

Only RNA with an integrity number ≥7 was used in the profiling studies. miRNAs were profiled in subjects with COPD (N=19) and normal smokers (N=8) using Exiqon miRNA microarrays according to the ...

Methods: Public datasets from six mRNA and three miRNA microarray datasets were downloaded from the GEO website to screen final differentially expressed genes (FDEGs) and hub genes in the heart, lung, ...

There were no significant differences in clinical, biochemical, haematological, virological, or histological characteristics between the 22 patients with HCV who were analysed by microarray and the 13 ...

The field of proteomics has undergone rapid advancements over the last decade and protein microarrays have emerged as a promising technological platform for the challenging task of studying ...

Parallel quantification of large numbers of messenger RNA transcripts using microarray technology promises to provide detailed insight into cellular processes involved in the regulation of gene ...

Fragments of the wild-type or mutant 3’-UTR of PDZK1 containing miR-128-3p binding domains were cloned into the pmirGLO Dual-Luciferase miRNA Target Expression Vector. According to the manufacturer’s ...

College of Chemistry and Molecular Sciences, Department of Colorectal and Anal Surgery of Zhongnan Hospital of Wuhan University, Clinical Center of Intestinal and Colorectal Diseases of Hubei Province ...

Encouragingly, the concept of miRNA-based therapeutics is developing, with synthetic antagonists of miRNAs (antagomiRs) currently in phase II trials for the treatment of chronic hepatitis C virus ...