Researchers have identified a key role microglia play in melanoma brain metastases progression and mechanisms to target them.

at immune cells known as microglia. Vital in both developing and mature brains, these cells help shape neurons, control how they communicate, keep an eye out for pathogenic intruders, and mediate ...

I mmune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and ...

Wu and colleagues confirmed that cultured-microglia-carrying lipid droplets struggled with phagocytosis, poorly engulfing ...

Pexidartinib or PLX3397 is an enzyme inhibitor commonly used to remove microglia in the lab setting to help researchers better understand the role of these cells in brain health, function ...

The study, published in Cell Death Discovery, revealed that aged microglia exhibit altered gene expression and a weakened immune response compared to their younger counterparts.