Nwd1 gene deletion triggers MASH-like pathology in mice
Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated ...
Frontiers5d
Elevated levels of IRF1 and CASP1 as pyroptosis-related biomarkers for intestinal epithelial cells in Crohn’s disease
The enriched KEGG pathways were those of NOD-like receptor signaling, necroptosis, influenza A, lipid and atherosclerosis ... suggest potential crosstalk between IECs and monocyte/macrophage ...
C&EN22d
Hydrotalcites-Induced Pyroptosis Combined with Toll-Like Receptor Activation Elicited Dual Stimulation of Innate and Adaptive Immunity
School of Pharmacy, Faculty of Medicine, Macau University of Science and Technology, Taipa, Macau SAR 999078, China Macao Institute of Materials Science and Engineering, Macau University of Science ...
Healio23d
High prevalence of atherosclerosis detected in patients entering lung cancer therapy
Patients with lung cancer have a high prevalence of atherosclerosis. These patients may benefit from calcium scoring. Researchers identified specific risk factors linked to atherosclerosis in this ...
Frontiers27d
Macrophage pyroptosis and its crucial role in ALI/ARDS
However, the pathogenesis of ALI/ARDS remains a complex issue. In recent years, the role of macrophage pyroptosis in lung injury has garnered extensive attention worldwide. This paper reviews the ...
ahajournals.org27d
Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression
To uncover age-related alterations that may impair atherosclerosis regression, we investigated the response of young and old macrophages to atherogenic lipoproteins in vitro and in vivo. Metabolic and ...
Medical Xpress28d
Discovery of macrophages' protective role for nerve damage opens new treatment path
One type of immune cell residing in nerves, a pro-inflammatory macrophage, began producing chemokines. These signaling molecules recruited a second population of circulating macrophages ...