Explore how cutting-edge agents like alpelisib, capivasertib, MEK and ERK inhibitors, and JAK inhibitors are reshaping the ...

Briony takes a look at the new Zotac MEK1 Mini PC - a system that promises to bring great gaming performance in a small, console sized chassis. The big question - is it really worth the £1399 asking ...

as well as experimentally validated MEK1/2 pathway genes. These data suggest more robust and durable MEK inhibition by PAS-004 under inflammatory conditions. The study found that PAS-004 provided ...

as well as experimentally validated MEK1/2 pathway genes. These data suggest more robust and durable MEK inhibition by PAS-004 under inflammatory conditions. : At all doses, PAS-004 showed greater ...

REC-4881 (MEK1/2): Preliminary data presented at DDW as a late-breaking oral presentation on May 4, 2025 from the ongoing Phase 1b/2 TUPELO study of REC-4881 in familial adenomatous polyposis (FAP ...

It affects approximately 100,000 children and adults in the US. The MEK1 and MEK2 inhibitor showed that it was able to reduce NF1-PN lesions in the 114-patient phase 2b ReNeu trial, with an ...

Coming after Ogsiveo at SprongWorks is Gomekli (mirdametinib), an oral small molecule designed to inhibit MEK1 and MEK2 proteins, which has been submitted for FDA approval as a treatment for ...

MYC amplification and protein expression as prognostic markers in pediatric and young adult osteosarcoma. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not ...