3D). Implementing aspects of the four lines of work described above, a chosen target region in mouse genomic DNA was amplified to be present in one of every six colonies on selection plates (Fig.

DNA recombination is the exchange of DNA strands to produce new nucleotide sequence arrangements. Recombination occurs typically, though not exclusively, between regions of similar sequence by ...

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, 117997 Moscow, Russia, and Institute of Molecular and Atomic Physics, Nezavisimosti av. 70, 220072 Minsk, Belarus * ...