Signaling is initiated by the binding of Wnt to a Frizzled receptor as well as a low-density lipoprotein receptor-related protein (LRP) coreceptor (e.g., LRP5) but is inhibited by the binding of ...

Newly granted patent is part of the expanding intellectual property portfolio directed to: -generating novel and selective Wnt surrogate molecules with potentially broad therapeutic utility and ...

This contribution is part of the special series of Inaugural Articles by members of the National Academy of Sciences elected in 2020. Contributed by Sean J. Morrison, April 16, 2021 (sent for review ...

Semaglutide promotes the proliferation and osteogenic differentiation of bone-derived mesenchymal stem cells through activation of the Wnt/LRP5/β-catenin signaling pathway Yawei Tian Huiming Liu ...