Myc-associated zinc finger protein (MAZ) was a regulator of both PGR and RPS6KA1. Additionally, KCNQ1OT1 and chr22-38_28785274-29006793.1 were found to jointly regulate PGR and RPS6KA1 through various ...

Methylation at the imprinted differentially methylated regions (DMRs) of chromosome 7 and 11 (GRB10 alt-TSS DMR (7p12); MEST alt-TSS DMR (7q32), H19/IGF2 IG-DMR (or IC1, 11p15), KCNQ1OT1 TSS DMR (or ...

Background Heterogeneous molecular defects affecting the 11p15.5 imprinted gene cluster are associated with the opposite growth disorders Beckwith-Wiedemann Syndrome (BWS) and Silver Russell syndrome ...

Background: Multiple sclerosis (MS) is a chronic neuroinflammatory disorder characterized by demyelination and immune dysregulation, and microglia play a central role in disease progression. Despite ...