Presynaptic NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role.

Scale bars: 5 ms, 0.1 mV. (B) For this sample connection, the JNK2-blocker SP600125 (Bennett et al., 2001) abolished tLTD (after/before = 99%, p = 0.86). Scale bars: 5 ms, 0.2 mV. (C, D) Ensemble data ...

Notably, JNK1 and JNK2 play distinct functional roles in various cancers. Specific inhibition of JNK2 increases the oncogenic potential of pancreatic cancer cells, whereas inhibition of JNK1 has the ...

Department of Pharmaceutical/Medicinal Chemistry, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, DE, Germany ...

OYSTER BAY, N.Y. — Some places seem to communicate with you when you visit. Not audibly, of course, but they somehow impart the echo of a life lived long ago. That’s the feeling I get at ...

The heart utilizes large amounts of fatty acids as energy providing substrates. The physiological balance of lipid uptake and oxidation prevents accumulation of excess lipids. Several processes that ...

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