Ivashkiv and colleagues show that IL-10 inhibits the expression and DNA binding of IRF1 and IRF5, two transcription factors that have an amplifying role in the induction of inflammatory NF-κB ...

Three machine learning algorithmssupport vector machine recursive feature elimination (SVM-RFE), least absolute shrinkage and selection operator regression (LASSO), and random forest (RF)-identified ...

Priming is mediated by pathways and mechanisms used in inflammatory signaling, including a stable STAT1 and IRF1 occupancy and histone acetylation. This priming process also makes cells more ...

Clinical outcomes and characterization of HER2 alterations in non-small cell lung cancer (NSCLC). This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a ...