STAT6 is a key transcription factor within the IL4/IL13 signaling pathways which act as drivers of inflammation in allergic conditions Nurix to receive a $15 million license extension fee from ...

The molecule replicated the selectivity of IL4/IL13 biologics by preventing differentiation of Th2 (T helper 2) cells without impacting other immune pathways. In a preclinical model of allergic ...

This year, we plan to have two, LRRC15 or 6201 and 1503, which is IL13/31 for atopic dermatitis. And so it just so happened that these two are internally discovered, but that doesn't necessarily ...

STAT6 is a key transcription factor within the IL4/IL13 signaling pathways which act as drivers of inflammation in allergic conditions ...

Dupixent is a first-in-class biologic that inhibits the signaling of the interleukin-4 (IL4) and interleukin-13 (IL13) pathways and the program focuses on a specific population of people with evidence ...

Se+ pHMOs-pre-exposed moDCs instructed T cells to produce type 2 cytokines like IL13. Se- pHMOs reduced the %CD86+ moDCs but did not drive a type 2 signature in T cells. In the presence of BLG, Se+ ...

For example, the claimed purity of IL2 is ≥95%. HPLC analysis of IL2 (a commercial product) and IL13 received from Professor Kakiuchi showed some impurities in IL2 but practically no impurities in ...