and modulate innate immune responses to bacterial and viral infections that involve the activation of IFN-regulatory factor 3 (IRF3), IRF7 and nuclear factor-κB (NF-κB). Two TRIM proteins ...

In recent years, protein arginine methyltransferases (PRMTs) have emerged as new members of a gene expression regulator family in eukaryotes, and are associated with cancer pathogenesis and ...

Notably, IRF3 displayed high gene expression across heterogeneous populations of the HS epidermis (SI Appendix, Fig. S7A). Subsequently, we investigated whether the inactivity of IRF3 could repress HS ...