The last few years have provided us with a new level of understanding of how chromosomes are replicated, segregated and read - and how their 3D organisation influences expression of individual genes ...

The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

1 Biomedical Center Munich (BMC), Physiological Genomics, LMU Munich, 82152 Planegg-Martinsried, Germany. 2 Institute of Stem Cell Research, Helmholtz Center Munich, BMC LMU Munich, 82152 ...

In the past two days, Lupin stock has surged 8 per cent after the pharmaceutical company received tentative approval from the US Food and Drug Administration (USFDA) to market generic HIV combination ...

When this muscle is irritated or triggered, your vocal cords close quickly, and you involuntarily suck in air, leading to the "hic" sound that hiccups are known for. Experts aren’t sure exactly why ...

This important study presents genome-wide high-resolution chromatin-based 3D genomic interaction maps for over 50 diverse human cell types and integrates these data with pediatric obesity GWAS. The ...

Epigenetic and transcriptomic datasets of primary FLS samples were generated using ChIP-seq, ATAC-seq, RNA-seq, cap analysis gene expression sequencing (CAGE-seq), and chromatin conformation analysis ...

followed by integrative analysis of HiC, ATAC-seq, RNA-seq and TCGA data. Conclusion: These data uncovered a close connection between 3D genome reorganization, chromatin accessibility as well as gene ...