Through the usage of high throughput chromatin conformation capture technology (Hi-C ... In this manuscript, the authors use HiC to study the 3D genome of CD14+ CD16+ monocytes from the blood of ...

How the 1D chromatin state and 3D chromatin architecture support this ... considering TADs from all treatments and parameterizations. Loops were detected with HiC Explorer hicDetectLoops with ...

The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

Chromatin is one of the most complex materials in cells and enables the massive amount of DNA in the genome to fold up and fit into the nucleus of each cell. The building blocks of this genetic ...

In the past two days, Lupin stock has surged 8 per cent after the pharmaceutical company received tentative approval from the US Food and Drug Administration (USFDA) to market generic HIV combination ...

1 Biomedical Center Munich (BMC), Physiological Genomics, LMU Munich, 82152 Planegg-Martinsried, Germany. 2 Institute of Stem Cell Research, Helmholtz Center Munich, BMC LMU Munich, 82152 ...

The last few years have provided us with a new level of understanding of how chromosomes are replicated, segregated and read - and how their 3D organisation influences expression of individual genes ...

When this muscle is irritated or triggered, your vocal cords close quickly, and you involuntarily suck in air, leading to the "hic" sound that hiccups are known for. Experts aren’t sure exactly why ...