Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatic musculoskeletal disease that predominantly affects the ...

Although HLA-B27-positive uveitis is the most common form of intraocular inflammation, there is no established therapeutic strategy to prevent recurrence. Before TNF inhibitors became available ...

Women with axial spondyloarthritis are less likely than men to respond to multiple different classes of advanced therapies, ...

The strongest risk factor for developing ankylosing spondylitis involves carrying the HLA-B27 gene variant, found in approximately 90% of people with the condition. However, only 5% of people who ...

This case study describes an atypically severe attack of uveitis in a patient with HLA-B27-positive ankylosing spondylitis. Although TNF-inhibitor therapy was extremely effective regarding ...

Patients with juvenile idiopathic arthritis (JIA) who carried the HLA-B27 genetic marker tended to have worse long-term outcomes, including lower rates of drug-free remission, in a prospective ...

including HLA-B27 and HLA-DR4, with similar results. “Biomarker discovery is rapidly advancing, but signatures remain heterogeneous, highlighting the need for standardized approaches,” Abdel ...

Those with spondyloarthritis and Crohn's, for example, may have changes in the HLA-B27 gene, which relates to a protein on white blood cells. This protein can cause your immune system to attack ...

Objective Human leucocyte antigen (HLA) B27 and HLA-B15 are associated with spondyloarthritis (SpA). Recent Assessment of SpondyloArthritis international Society (ASAS) criteria emphasise a ...

Background Different subtypes of HLA-B27 have a special positive association with some clinical features of AS.HLA-B*2705-positive patients had a higher incidence of uveitis.however,whether AS ...

Objective: To use MRI to study the sacroiliac joint (SIJ) and lumbar spine (LS) and explore the relationship between sites and extent of inflammation and HLA-B27 status over 12 months. Methods: 54 ...