In summary, the discovery of HDAC1's dual role in tumor suppression and promotion presents a nuanced understanding of T-cell lymphomas. As the medical community continues to refine treatment ...

Specific protein 1 (Sp1) is a member of the Sp/Kruppel-like factor family, which regulates cellular processes of neurons in the nervous system. This study was performed to examine the regulatory role ...

Unhealthy diets are a major impediment to achieving a healthier population in the United States. Although there is a relatively clear sense of what constitutes a healthy diet, most of the US ...

EPB41L4A-AS1 is a complex lncRNA gene. The EPB41L4A-AS1 locus is ∼2 kb (kilobases) long, and the main transcribed isoform terminates ∼300 nt from the 3’ end of the main isoform of the convergently ...

In target-based drug discovery, quantification of target engagement is required to build structure–activity relationships and develop a potent clinical candidate. Target engagement data also provides ...

Fig. 1 The interaction between PA28γ and C1QBP. (A, B) The interaction between endogenous PA28γ and C1QBP in HSC-3 cells was verified via immunoprecipitation (IP).(C) PLA image of UM1 cells shows the ...