DREAMseq: A phase III trial of treatment sequences in BRAFV600-mutant (m) metastatic melanoma (MM)—Final clinical results. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...

A first-in-human study of DYP688, an antibody drug conjugate delivering a direct Gq/11 inhibitor, in patients with metastatic uveal melanoma (MUM) and other GNAQ/11 mutant melanomas.

GNAQ and GNA11 encode members of the q class of G-protein α-subunits involved in mediating signals between G-protein-coupled receptors (GPCRs) and downstream effectors. To investigate whether ...

10 Somatic mutations in codon 209 of GNAQ, a gene encoding the signaling protein G-protein α subunit q, may be present in up to 80% of BN. 10 The difficult distinction of ACBN from melanoma associated ...

Graduate Institute of Biomedical Optomechatronics, College of Biomedical Engineering, Taipei Medical University, Taipei 11031, Taiwan School of Biomedical Engineering, College of Biomedical ...

Liquid biopsies using circulating tumour DNA (ctDNA) have emerged as an alternative to conventional biopsies. They can be used to aid in diagnosing and selecting an agent for treatment and can ...