Weighted gene co-expression network analysis prioritized seven hub genes. A random forest model incorporating six key feature genes (GLUL, DDX28, NCL, RIOK1, SUV39H1, RRS1) demonstrated robust ...

Viral-mediated Oct4 overexpression induces direct conversion of wildtype mammalian Müller glia to bipolar neurons, and this process is synergistically enhanced by loss of Notch signaling.

Potent antitumor activity of the KRASG12D inhibitor MRTX1133 in pancreatic cancer: Augmenting the nanoparticle-paclitaxel chemotherapy response. This is an ASCO Meeting Abstract from the 2025 ASCO ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. In the early phase of Alzheimer’s disease, ...

Hepatoblastoma (HB), the most common pediatric liver malignancy, is characterized by aggressive growth and metastasis driven by complex angiogenic mechanisms. This review elucidates the pivotal role ...

CAS CEMCS-CUHK Joint Laboratories, New Cornerstone Science Laboratory, State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and ...

Background A rise in paediatric cases of acute hepatitis of unknown origin (AHUO) was observed in 2022, some requiring liver transplantation. A link to adeno-associated virus 2 infection and CD4 + ...