The OCEANIC-AF trial has raised concerns about factor XI inhibitors. Should physicians still bet on this class of ...

Also, Nintendo Switch 2 launches into a changed market where players have come to expect that they will be able to carry their game libraries forward from one machine to another, which precluded a ...

Novo Nordisk today announced interim results from the phase 3 FRONTIER3 trial of 70 children (aged 1-11 years old) with haemophilia A with and without inhibitors. The trial initially assessed ...

Adjusted-dosage warfarin 2.1 a p < 0.0001 for noninferiority to enoxaparin. b p = 0.017 for noninferiority to enoxaparin. c p = 0.0003 for noninferiority to enoxaparin. d Values failed to show ...

This bridging replaces factor VIII, restoring thrombin production and clotting ability. The open-label, 2-part phase 3 FRONTIER3 trial (ClinicalTrials.gov Identifier: NCT05306418), evaluated the ...

Attribution (BY): Credit must be given to the creator. Percutaneous coronary intervention administration of statins enhances the thrombin–thrombomodulin (TM) interaction, which is critical for the ...

Methods: Two cohorts of patients with acute ischemic stroke treated with thrombolysis were recruited (cohort 1 n=36 patients, cohort 2 n= 42). Thrombin generation was determined by thrombin generation ...