ATP-competitive small-molecule inhibitors of CDK5, GSK3β and ERK2 can modulate tau phosphorylation in vitro. By exploiting the structural differences within the ATP-binding pocket of these ...

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Cardiovascular defects, injuries, and degenerative diseases often require surgical intervention and the use of implantable replacement material and conduits. Traditional vascular grafts made of ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cells change their metabolic profiles in ...

This study presents an important practical modification of the orthogonal hybridization chain reaction (HCR) technique, a promising yet underutilized method with broad potential for future ...

This study focuses on the role of a T-cell-specific receptor, ctla-4, in a new zebrafish model of IBD-like phenotype. Although implicated in IBD diseases, the function of ctla-4 has been hard to study ...

Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking ...

This cover highlights the article Molecular insights into the effect of 1,6-hexanediol on FUS phase separation by Tongyin Zheng, Noah Wake, Shuo-Lin Weng, Theodora Myrto Perdikari, Anastasia C. Murthy ...

Objective: Diabetic liver injury, a chronic complication of diabetes mellitus (DM), has been extensively documented. Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, has shown ...

M. El-Sobky, R. Rijal, R. Gomer, Collected data for polyphosphate chemorepulsion. Figshare. https://figshare.com/s/27dcc330cb24d1a33c17. Deposited 21 March 2025.