Explore how cutting-edge agents like alpelisib, capivasertib, MEK and ERK inhibitors, and JAK inhibitors are reshaping the ...

Here they show that heterodimerization of the receptor tyrosine kinases PDGFRa and PDGFRb negatively affects downstream ERK1/2 signaling and cellular proliferation, due in part to rapid ...

A new preclinical study published in Frontiers in Immunology finds that cannabidiol (CBD) may help slow the growth of HPV-positive head and neck squamous cell carcinoma (HNSCC) by activating the ...

† † Biomedical Research Institute and # Intellectual Property Division, Research and Innovation Promotion Headquarters, National Institute of Advanced Science and Technology (AIST), Tsukuba, Ibaraki, ...

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New research from Zhejiang University reveals that the CTLA-4 gene helps regulate the immune system to prevent chronic gut ...

The newly generated CD4 single-positive (SP) T lymphocytes are featured by enhanced IL-4 but repressed IFN-γ production. The mechanisms underlying this functional bias remain elusive. Previous studies ...