Cymbalta (duloxetine) can cause a range of side effects when you stop taking it, especially if you discontinue it abruptly. This is known as a withdrawal or antidepressant discontinuation syndrome.

For diabetic peripheral neuropathic pain, the recommended dosage is 60 mg per day, although dosages of up to 120 mg daily have been studied. [25] Higher dosages do not have proven benefit and may ...

In this study, the safety and efficacy of duloxetine, a potent dual reuptake inhibitor of 5-HT and NE, were examined. Results: The rate of discontinuation due to adverse events was 11.3%.