Researchers at Vanderbilt University identified a molecular approach to extend the antidepressant effects of ketamine in mice by applying BCI, a compound that inhibits DUSP6 to sustain ERK pathway ...

Response adapted oncologic surgery following neoadjuvant immunotherapy and chemotherapy for resectable locally advanced oral cavity and oropharyngeal squamous cell carcinoma. Comparison of survival ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Nuclear factor erythroid 2-related factor 2 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Proteins operate within dense interconnected ...

Communicated by Kevan M. Shokat, University of California, San Francisco, CA, June 28, 2010 (received for review April 16, 2010) PLX4032 Inhibits MEK and ERK Phosphorylation Only in Tumors with BRAF ...

Introduction: Pseudorabies virus (PRV) is a herpesvirus that can infect domestic animals, such as pigs, cattle and sheep, and cause fever, itching (except pigs), and encephalomyelitis. In particular, ...

m 6 A is the most common RNA epigenetic modification, which can affect RNA folding, stability, degradation, etc., thereby participating in splicing, translation, apoptosis, and other processes (1).

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