Chromatin fiber's genomic 'memory' governs the building blocks of life, study reveals
Northwestern Medicine scientists have discovered new details about how the human genome produces instructions for creating ...
The EMBO Journal7h
A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine
A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...
Science Daily3d
Spliceosome: How cells avoid errors when manufacturing mRNA
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...
News Medical5d
Researchers discover how RNA molecules influence multiple generations
RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA ...
eLife5d
Transcriptional antitermination integrates the expression of loci of diverse phage origin in the chimeric Bartonella Gene Transfer Agent BaGTA
This manuscript describes an important finding of the transcriptional control of a chimeric gene transfer agents (GTA) cluster in Bartonella by a processive anti-termination factor (BrrG). The ...