CREST syndrome, or limited systemic sclerosis, is a rare autoimmune disease that causes changes and scarring of the body's blood vessels and connective tissues. The acronym CREST stands for the main ...

Because this mechanism appears to enhance experimental autoimmune encephalomy-elitis in wild-type mice, it might be a general etiologic process underlying other Th17 cell-mediated autoimmune diseases ...

Dysregulation of the balance between effector and regulatory T cells causes immunological disorders such as allergy and autoimmune diseases. We have discovered SOCS family proteins, which play pivotal ...